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16,51 The anxiolytic effect of GLP-1 agonists has been hypothesized due to the preservation of brain-derived neurotrophic factor/nuclear factor erythroid 2related factor 2 levels, decreased oxidative stress, and lipocalin 2 levels in the hippocampus

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"Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications." Current Neuropharmacology, 2016;14(8):857-865

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(PubMed) Secades JJ, Alvarez-Sabin J, Castillo J, et al

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3hj), but there was no significant difference in the ratio of p-SMAD3 to SMAD3 (data not shown)

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