Epithalon Primary focus: Pineal regulation Melatonin Biological aging Menopause sleep disruption Epithalon is a tetrapeptide (Ala-Glu-Asp-Gly) that mimics epithalamin, a peptide extract from the pineal gland
The peptide improved healing in both ischemic and diabetic wound models (rats and pigs), producing organized collagen fiber alignment rather than random scarring (Pickart & Margolina, 2018)
Current compounding status As of March 2025, the FDA determined that the tirzepatide shortage is resolved, which impacts compounding eligibility
It is typically more suitable for lighter skin types and requires proper assessment to determine appropriateness
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Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation