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The Journal of Clinical Endocrinology and Metabolism

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A study from the University of Pennsylvania and Cedars-Sinai Medical Center found a 700% increase in use of the drugs for patients without diabetes from 2019 to 2023

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Recent studies suggest that treatment with semaglutide (GLP-1RA) in combination with firsocostat (ACC-a inhibitor) and/or cilofexor (nonsteroidal FXR agonist) can further improve hepatic steatosis and thus NAFLD compared with semaglutide alone in exploratory efficacy analyses [113]

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