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demonstrated that in dendritic cells (DCs), LPS-induced glycolysis is repurposed to replenish citrate, an intermediate metabolite in the TCA cycle that is depleted for the de novo synthesis of fatty acids (12)

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Intranasal offers convenience and potentially faster central effects

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A 30 mg vial used over five weeks at 6 mg per week experiences five punctures

In a study on the efficacy and safety of catalpol in the treatment of postoperative patients with locally advanced colon cancer, patients treated with an intraperitoneal injection of 10 mg/kg catalpol twice a day for 12 weeks, monitoring patients appeared with adverse reactions of diarrhea, nausea, vomiting, gastrointestinal ulcers, allergy, constipation, alopecia, and peripheral neurotoxicity