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The justification for their nomenclature has been questioned on the basis of their low affinity for IGFBPs, questionable ability to significantly influence IGF effects and the fact they share limited phylogenetic relationship with other members of the family [25]

GPX4 is essential for embryonic development

Revisiting the global overfat pandemic

228 Its promising multi-pathway effects make quercetin a widely used dietary supplement, 229 and further structural optimization may enhance specificity and stability for therapeutic development

Medications like methylphenidate, which primarily target dopamine and norepinephrine, are effective in improving symptoms in around 60-70% of patients

doi:10.1093/humupd/dmu006