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Chemogenetic manipulation To manipulate the activity of specific neurons, mice expressing chemogenetic viruses were intraperitoneally injected with CNO (2 mg/kg, APExBIO Technology LLC, Cat

muciniphila Recently, GLP-1 medications have taken the spotlight for their abilities to manage T2DM and reduce body weight in overweight and obese individuals

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Key findings from this trial (PMID: 37350954) included: At 48 weeks, the 12 mg dose produced a mean weight reduction of 24.2% from baseline, compared to 2.1% in the placebo group

Katkat et al, 2023