Their rapid adoption underscores just how quickly the treatment paradigm has shifted
This is likely because GLP-1 agonists can delay the emptying of bile from the gallbladder
Even telling yourself you shouldnt eat certain foods can increase food noise, cravings, and overeating or bingeing
The scale might barely move, but insulin sensitivity, inflammatory markers, and liver function can transform
This class of medications contains the popular semaglutide (Ozempic, Wegovy, Rybelsus), tirzepatide (Mounjaro, Zepbound), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and exenatide (Byetta, Bydureon)
The Ozempic prescribing information includes a warning about acute kidney injury and worsening of existing kidney problems, and states that "a majority of the reported events occurred in patients who had experienced nausea, vomiting, diarrhea, or dehydration." The same label tells doctors to counsel patients "of the potential risk of dehydration due to gastrointestinal adverse reactions and take precautions to avoid fluid depletion." The Mounjaro label carries the same class warning and advises doctors to "monitor renal function in patients reporting adverse reactions to MOUNJARO that could lead to volume depletion." It helps to keep this in perspective
