In high doses, catechins and specifically EGCG causes acute hepatocellular injury in mice and rats, but the equivalent dose in humans (30-90 mcg/kg) is considerably higher than is usually administered in typical weight loss products (3-12 mg/kg)
This article was reviewed by Adrienne DePaul, MS, RDN
[DOI] [PubMed] [Google Scholar] 296.Li J, et al
According to the Joi + Blokes website, this hormone "plays a crucial role in blood sugar regulation by stimulating insulin release and lowering glucagon levels." The FDA-approved finished drug versions of semaglutide are approved for specific indications including type 2 diabetes management (Ozempic) and chronic weight management (Wegovy) in specific patient populations
This dual-action effect not only helps control cravings but also promotes fat loss
Tew KD, O'Brien M, Laing NM, Shen H