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Ethics declarations Competing interests M.J.D has acted as a consultant, advisory board member and speaker for Boehringer Ingelheim, Eli Lilly, Novo Nordisk and Sanofi

By doing so, these treatments reduce the constant urge to overeat and help individuals feel completely satisfied with much smaller portions

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To further characterize these interactions, we constructed a molecular interaction network (Figure 7C) revealed three functionally interconnected modules: (Young et al., 1990) an oxidative stress module linking Gpx3 with glutathione metabolites, and ( Consistent with multi-omics findings, KEGG pathway analysis identified glutathione metabolism as the most significantly perturbed shared pathway (Figure 8A), exhibiting coordinated changes between upregulated antioxidant enzymes such as Gpx3 and Mgst1 alongside depleted glutathione derivatives, supporting redox imbalance as a key pathogenic feature

J Prev Alzheimers Dis 12:100163

Joseph B