Older age : Due to changes in dietary nutrient intake (usually from eating less overall) and also decreased production of stomach acid, the elderly tend to have reduced levels of vitamin B12
Potassium is known to be in major shortfall in Western society, with a huge drop in intake (due to poor nutrition but also poor agricultural practices)
The final cost to patients depends on the type of insurance plan they have
It can bypass the regulatory control of glutathione homeostasis, and in a similar single-dose clinical study was shown to boost glutathione levels in white blood cells within 2 hours
BBA-Bioenerg 1857:665677 Ding SH, Lu QT, Zhang Y, Yang ZP, Wen XG, Zhang LX, Lu CM (2009) Enhanced sensitivity to oxidative stress in transgenic tobacco plants with decreased glutathione reductase activity leads to a decrease in ascorbate pool and ascorbate redox state
Merck & Co