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More Research Questions As researchers map GLP-1 receptor distribution, they are also searching for unifying mechanisms that could explain the drugs systemic effects

While some supplement ingredients have shown promise in limited studies related to metabolic health and weight management, they do not have the same effects as GLP-1 drugs, Ventura said

There have also been case reports of acute renal failure/renal insufficiency in patients using exenatide twice daily, though this was typically seen in the setting of severe gastrointestinal side effects causing dehydration [27-29]

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Research is ongoing to determine whether these drugs could help protect against neurodegenerative diseases like Alzheimer's