Airway epithelial-specific knockout of LONP1 in mice results in the loss of differentiation capacity of primitive airway progenitor cells into club cells and ciliated cells, instead driving their differentiation into dysfunctional luminal cells
Mantngase hidratado: Beba agua constantemente durante el da para mantener la hidratacin
If sleep is really a problem, a small dose of a tricyclic antidepressant with sedative effects (see antidepressants, above) is a possible option
Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J
Consistently, antioxidants and catalase show neuroprotective effects in individuals with DS and model mice 14,18
Berthet et al., 2009