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The 28-Day Rule Once reconstituted with bacteriostatic water, semaglutide is stable for up to 28 days refrigerated the same window as most other peptides

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Once-daily oral semaglutide was administered to test subjects diagnosed with type 2 diabetes in doses of either 2.5, 5, 10, 20, or 40 mg and compared to a placebo compound as well as a once-weekly subcutaneous administration of semaglutide