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Bioorthogonal chemistry plays a crucial role in conjugating proteins or peptides under biological conditions
Thus, ghrelin may be a potential treatment for acute insulin-induced hypoglycaemia in type 1 diabetes patients
On the other hand, reduced glutathione is broken down during digestion and absorbed as individual components
[1] When used in combination with sulfonylureas or insulin, there is an increased risk of hypoglycaemia, and dose adjustments of these medications may be required
When GHRP-2 binds to the GHS-R1a receptors on pituitary somatotrophs (the cells in the pituitary gland that produce GH), it directly signals them to secrete GH
Br J Haematol 122(6):10011008 Wambebe C, Khamofu H, Momoh JA et al (2001) Double-blind, placebo-controlled, randomised cross-over clinical trial of NIPRISAN in patients with Sickle Cell Disorder
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