Back DiMarchi, R Efendic, S (1997) 'Use of GLP-1 analogs and derivatives administered peripherally in regulation of obesity', US Patent US6191102B1.Back Drucker, DJ, Habener, JF, Holst, JJ (1 Dec 2017) 'Discovery, characterization, and clinical development of the glucagon-like peptides', Journal of Clinical Investigation , 127/12, 4217-27
The main side effects are gastrointestinal
They regained an average of 22 pounds in the first year with a projected estimate that they'd return to their original, pre-GLP-1 weight after 18 months
Although we need to do many more studies looking at muscle function as people go on GLP-1s like resistance training and squeeze my hand and sit-to-stand and quadricep extensions, all these things that we do to look at function
& Movassat, J
When I see the GLP-1 craze, I think about how peoples lives have been ruined by opioids like Oxycontin