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This damage is primarily from ultraviolet light exposure, either from the sun or artificial sources like tanning beds

While the animal model treated with PBS did not show any signs for ROS, high amounts of fluorescence signals in the tissue from the animal treated with NP4 were observed (Supplementary Fig

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Clinical Genetics

Treatment of Sun Damage Prolonged sun exposure can cause significant damage to the skin, leading to sunspots, discoloration, and premature aging