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These findings make it scientifically interesting, but they remain preclinical and cannot establish effectiveness in people

[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Heilbronn LK, de Jonge L, Frisard MI, et al

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Although primarily an AD model, these mice exhibit a robust neuroinflammatory profilemarked by pronounced astrogliosis and microglial activationthat may share common mechanisms with vascular contributions to cognitive impairment 144

Neurotox Res 25:8189 Quik M et al (2015) Alpha7 nicotinic receptors as therapeutic targets for Parkinsons disease