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Many patients experience reduced appetite and fluid intake when starting GLP-1 therapy, whilst the medicine's gastrointestinal effects including nausea and occasional vomiting can further affect hydration status

In simple words, it tells your brain: Im full, stop eating, and helps manage how your body uses and stores glucose

Major health publications now routinely list creatine alongside protein and HMB as a reasonable add-on for people on GLP-1 medications who want to preserve muscle

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Nevertheless, the peptide is under active research in phase 3 trials, and initial studies suggest that retatrutide could be as effective as tirzepatide in weight loss settings

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