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Untargeted or semi-targeted approaches, such as phospho-proteomic or kinomic analyses may be required to highlight agonist-related differences in global signaling networks, as for other GPCRs, such as the angiotensin II type 1 receptor 62

Patients experiencing this symptom should consider both medication-related and independent gastrointestinal causes, particularly if mucus is accompanied by other concerning features such as blood, significant abdominal pain, or persistent changes in bowel habits

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