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We further attempt to discuss the pathogenic and therapeutic implications of ferroptosis in different autoimmune diseases to identify possible diagnostic targets and therapeutic options

It was reclassified from FDA Category 2 (restricted) back to Category 1 (compoundable) following HHS Secretary RFK Jr.s announcement on February 27, 2026

[1] [4] Metformin first-line therapy for type 2 diabetes, though it more commonly causes diarrhoea rather than constipation

176 As an extensive discussion of these drugs is beyond the scope of this review, we refer the reader to the referenced work and focus our discussion on two less frequently mentioned interventions for which preclinical and clinical experience has been made by one of us (MKF)

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