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Osteophytes, though anatomically distinct from subchondral bone, are closely associated with its pathological changes in OA

These results confirm that decreases in intracellular GSH (and associated increased oxidative stress) worsen T2 inflammatory protein expression and secretion in HAECs, while increasing their susceptibility to ferroptotic death

Florenzano P, Ferreira C, Nesterova G, Roberts MS, Tella SH, de Castro LF, Brown SM, Whitaker A, Pereira RC, Bulas D, Gafni RI, Salusky IB, Gahl WA, Collins MT (2018) Skeletal consequences of nephropathic cystinosis

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