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In this study, glutamine flux was directed toward the generation of R-2-HG in IDH1/2 mutant cells, and the kinetics of R-2-HG formation were proportionally of the same order of magnitude as those of glutamate or -KG formation via glutaminolysis

2.6 Eye health Owing to its effects on microcirculation, inflammation and oxidation, Pycnogenol was found to have positive effects on eye health (45, 46)

Acknowledgements This paper was supported by grants from the National Nature Scientific Foundation of China (No: 81770639), Construction project of advanced clinical medicine, Capital Medical University (No.1192070312) and Beijing Municipal Science & Technology Commission (No

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One patient reported severe headache following intramuscular dosing