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Risk of bias was graded as unclear, high, or low

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Second, it is noteworthy that there was significant heterogeneity in patients with low cardiovascular disease risk (defined as those without severe cardiovascular diseases) across the included studies

type 2 diabetes (49%), the researchers observed a greater mean reduction in ALT by 32.9 U/L among those with diabetes ( P = .02)

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This option may be suitable for those who prefer slower titration or are starting with a lower dose