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People with hypothyroidism, hyperthyroidism, or medullary thyroid cancer history often wonder whether these medications are safe for them

This fear originated from preclinical data showing that these drugs could make thyroid C-cells proliferate in rodent models

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Funding This research did not receive any grant from the public, commercial, or non-profit funding agencies

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Unlike the conventional small molecule inhibitors, the PROTAC technology possesses its unique catalytic mode of action