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This peptide has been utilized in preclinical studies examining MC3R and MC4R receptor binding kinetics, hypothalamic melanocortin signaling pathways, CNS neuropeptide pathway interactions, and central receptor selectivity profiles in isolated cell models independent of the broader neurological effects associated with endogenous melanocortin activity

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This study established LONP1 as a key risk gene for CDH through multidimensional evidence and provided a novel biomarker for prenatal genetic diagnosis

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