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Do not reduce frequency until you have established steady-state blood levels and confirmed the medication is working
But note, not everyone experiences the large amounts of weight loss from GLP-1 RAs you may have heard about
Evidence indicates these agents induce significant weight loss, appetite suppression, and metabolic improvements via mechanisms independent of intact MC4R signaling
Cell Rep Med
& Kwan, A
Physical activity improves insulin sensitivity, enhances metabolic flexibility, and strengthens gut hormone signaling
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