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Cytosolic copper enters mitochondria through the cytosolic anionic ligand (CuL) complex or binds to copper chaperone proteins, including copper chaperone for superoxide dismutase (CCS), human antioxidant protein 1, and cytochrome c oxidase copper chaperone 17, before being transferred to copper-storing proteins such as COX1, copper metallothionein 1, and superoxide dismutase [Cu-Zn] (SOD1)
Supports cognitive health and a positive mood, particularly in the elderly
NAION happens when blood flow to the optic nerve is blocked, says Rachel Pessah-Pollack, MD, FACE, clinical associate director in the Division of Endocrinology, Diabetes & Metabolism at NYU School of Medicine
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Ferdous MR, Abdalla M, Yang M, Xiaoling L, Song Y