In the SELECT study, for example, 16.6 percent of participants receiving semaglutide dropped out of the trial because of adverse effects, mainly digestive problems such as nausea, vomiting and diarrhea
The source data underlying Figs
The World Health Organization issued a safety alert about one potential eye complication in June 2025 (WHO, 2025)
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To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig
Increased low-grade inflammation is a major risk factor for morbidity and mortality in older adults (3, 4) and a hallmark of aging-related comorbidities