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The International Journal of Dermatology explicitly states that IV glutathione is contraindicated due to lack of efficacy evidence and documented side effects, representing a strong cautionary stance from the dermatology community

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1) without increasing the incidence of arrhythmia or hospitalization or worsening heart failure [22, 40, 47,48,49,50,51,52,53,54]

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Evening dosing should occur 23 hours after dinner to avoid nutrient competition during the GH pulse window