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Using preclinical models of breast cancer, the team also found they could slow tumor growth by blocking the cancers ability to use glutathione

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Transsulfuration pathway provides an endogenous pathway for homocysteine conversion to antioxidant glutathione (GSH)

10.1053/j.gastro.2012.05.049 54 MonfeugaT.NorlinJ.BuggeA.GaalsgaardE

MTX-treated group MTX (5 mg/Kg b.w) was intraperitoneally injected to rats for five consecutive days 27