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Each body area has different subcutaneous thickness: the abdomen typically offers the most consistent fatty layer, while the outer thigh and upper arm provide reliable secondary sites

Those patients typically need either a full therapeutic dose or a surgical option like gastric sleeve or gastric bypass for durable results

The third approach combines lifestyle modifications established during treatment with strategic supplementation

Ergothione is exclusively obtained through the diet (beans, livestock products, or mushrooms) and is converted to TMA by degrading the enzyme ergothionase

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