It inhibits tyrosinase (the key enzyme that makes dark melanin) and shifts pigment synthesis toward lighter pheomelanin
doi: 10.1016/j.bbamcr.2013.08.003
Glaucoma may involve optic nerve head ischemia
Autoimmune gastritis (AIG), as a non-self-limiting chronic inflammatory disorder, leads to the destruction of parietal cells in the stomach, resulting in reduced acid output and loss of intrinsic factor, that results in malabsorption of vitamin B 12 and iron, which cause pernicious anemia and iron deficiency anaemia
High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma
Eating smaller meals, avoiding high-fat foods, staying hydrated, and dosing escalation protocols all reduce nausea rates in clinical trials and practice