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With respect to the aging process, insulin/IGF-1 signaling controls the activity of several longevity genes, such as mechanistic target of rapamycin (mTOR) and forkhead box O (FoxO) signaling [4, 5] (Fig

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(2022) demonstrated that IRT1 undergoes post-translational regulation via endocytosis in response to metal presence, confirming its pivotal role as a Cd 2 uptake route under Fe deficiency

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doi:10.1080/17471060701682260 51 Mundi MS, Shah M, Hurt RT