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A compensatory anti-inflammatory mechanism then typically follows (59), causing an imbalance in immune responses (58, 59) combined with hypothesised autoimmunity (30, 52, 85, 182)

Rotate your injection sites If soreness is localized to a previous injection site, that is a sign to give the area a break

Segel, M

Clinical trials, such as the SURMOUNT-1 study, have shown that tirzepatide may lead to a higher average percentage of weight loss compared to semaglutide

& Schroder, K

Your prescriber should establish: Baseline measurements : Weight, blood pressure, mood assessment, and relevant blood tests Follow-up schedule : Regular appointments to monitor progress, side effects, and treatment response Target outcomes : Specific, measurable goals for both weight management and smoking cessation Duration of treatment : Wegovy is typically prescribed for up to 2 years in the NHS