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Supplementation with L-carnitine was found to prevent that reduction in plasma carnitine levels that was observed in the women in the placebo group
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Add hypotension and sinus tachycardia (2 to 4 bpm mean increase) to side effect profile
And importantly, clinicians should remain open to considering rare diagnoses like ROHHAD when the phenotype includes hypoventilation, autonomic dysregulation, or extreme hyperphagia. Perhaps one of the most exciting takeaways is that this patients hyperphagia improved markedly (and likewise quickly worsened during medication interruptions), suggesting that some of her hyperphagia was being modulated by GLP-1 RA therapy