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doi: 10.1097/MOH.0b013e328345a3d1 11 WoodfinAVoisinMBBeyrauMColomBCailleDDiapouliFMet al

Some studies have evaluated AOD 9604 in combination with other compounds, such as hyaluronic acid, to assess interactions between structural support systems and peptide-mediated signaling

Retatrutide appears more aggressive mechanistically because it activates three receptor pathways

So the move is not to replace an LDL-C target with a more aggressive apoB one