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The FDA prescribing information includes a boxed warning for risk of thyroid C-cell tumors and contraindication in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

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Tirzepatide, although not purely a GLP-1 receptor agonist, also delays gastric emptying and should be included in perioperative medication screening

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