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However, NK cells activation is greatly inhibited due to the overproduction of transforming growth factor (TGF-) and other anti-inflammatory cytokines and chemokines in the TME (71, 72)

Mangalam A, Shahi SK, Luckey D et al (2017) Human gut-derived commensal bacteria suppress CNS inflammatory and demyelinating disease

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Under an increase in GSH/GSSG, Grx can catalyze the deglutathionylation of proteins, but under conditions of decreased GSH/GSSG ratio, Grx can catalyze S-glutathionylation of proteins

doi: 10.1186/s12951-022-01653-w 298 JadiPKDaveAIssaRTabbasumKOkurowskaKSamarthAet al