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2 Symptoms range from mild self-limiting conditions to life-threatening hemodynamic instability 3 (Figure 2)

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However, this particular dose is indicated for sleep-related pathologies such as jet-lag and works by targeting the central nervous system where canonical melatonin receptors are abundantly expressed (69)

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doi: 10.1089/neu.1998.15.599

BMC Genomics 15 , 620 (2014)