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The molecule is permeable to cell membranes (confirmed by Caco-2 assay) and highly selective, without inhibitory effect on other SAM-dependent methyltransferases

The abdominal region is the preferred injection site, though thighs and upper arms are acceptable alternatives

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observed in Nature Medicine , NNMT inhibition in adipose tissue produced favorable body composition changes without negatively impacting muscle mass (Kraus et al., Nature Medicine )

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Lot-Linked COAs : Each vials lot number ties directly to third-party HPLC/MS results