Barkmeier AJ, et al
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When treating people with diabetes who need insulin, semaglutide injections are not used instead of insulin
The results showed that in high risk patients with T2D liraglutide reduced the risk of MACE by 13% (primary endpoint included cardiovascular death, non-fatal myocardial infarction (MI), and non-fatal stroke) ( In the ELIXA and the EXSCEL trials, GLP-1RAs (once daily lixisenatide and once weekly exenatide, respectively) didnt provide benefit in MACE reduction compared to placebo, but were non-inferior to placebo for the primary composite outcome of MACE
Before and during therapy, many clinicians in India increasingly recommend: Baseline and periodic kidney and liver tests Pancreatic enzymes where indicated An eye examination in diabetic patients An abdominal ultrasound in those at higher gallbladder risk What top experts and recent studies are saying Reviews in international journals stress that GI side effects are common but usually manageable, and that long-term benefits in diabetes and heart disease are substantial when the drugs are used correctly
and slow gastric emptying, leading to weight loss, which is beneficial for diabetic patients who are obese
