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Of note, exendin-4 was serendipitously discovered in the saliva of the Gila monster ( Heloderma suspectum ) and was revealed to be a GLP-1 analog that is resistant to DPP-4 action in 1992, even before the mechanism of GLP-1 degradation was identified [7]

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The role of insulin and blood sugar control Beyond appetite regulation, GLP-1s create a powerful effect on blood sugar management

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