Its high reactivity limits its diffusion, causing damage to macromolecules like cell membranes, proteins, and DNA [55, 56]
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It is important to recognize that these reports are anecdotal and not substantiated by large scale clinical trials
S2.4 Comparison between HH curves, pHp, and amount of niclosamide in solution To complete this theoretical assessment, plotted in Figure S5 (red symbols) is the pHp curve, giving the maximum amount of niclosamide expected to be in solution (uM) versus the solution pH (right axis) using the values derived from experiment of pKa = 6.87, S o = 1.77uM
This matters most for people whose bodies struggle to absorb B12 from food or pills
E., Muir, T