tirzepatide and trt + ~6 months : r/trt Tirzepatide and TRT / 70

Shi et al

The Bottom Line A Hone Health survey suggests many people are already using peptides the FDA is considering reclassifying

In 72-week clinical trials, people taking Mounjaro at doses up to 15 mg lost an average of 22.5% of their starting weight

Some state programs cover semaglutide and tirzepatide for weight management in patients with obesity, while others restrict coverage exclusively to patients with concurrent type 2 diabetes diagnosis

Parkinsons disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

This is not inherently problematic for a new product, but it means we are working with preliminary evidence rather than established clinical proof