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Although certainty of existing evidence was low, adverse events were uncommon and mild, supporting further high-quality clinical trials

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Consistently with prior studies of L-carnitine administration in mice (Koeth et al., 2014), in our study, we observed that peripheral GBB, and to a lesser extent crotonobetaine, increased in mice after L-carnitine oral challenge but not TMAO

OBrien Laramy MN, Luthra S, Brown MF, Bartlett DW