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doi: 10.1016/0031-9384(82)90098-1

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The standard titration approach The clinical trials used specific escalation protocols designed to minimize GI disturbance while still reaching therapeutic dose levels

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Managing Side Effects and Expectations in Post-Bariatric GLP-1 Use GLP-1 side effectsnausea, constipation, vomitingmay feel amplified after bypass due to reduced stomach size and delayed gastric emptying