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doi: 10.1001/jamainternmed.2015.59

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In hepatocytes, triiodothyronine (T3) binding to THR- stimulates -oxidation, increases LDL receptor expression, improves mitochondrial function in hepatic cells, boosts very-low-density lipoprotein (VLDL) secretion, and enhances reverse cholesterol transport, thereby reducing lipotoxicity and inflammation [3, 16]

doi:10.1096/fj.13-230227

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Localized application focuses on injured areas (tendon strain, muscle tear), while systemic use supports overall recovery balance