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Biologic exclusivity at 12 years reflects the structural complexity of large-molecule manufacturing and the higher development cost of biologics

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[Google Scholar] Pearson MJ, Herndler-Brandstetter D, Tariq MA, Nicholson TA, Philp AM, Smith HL, et al

This study showed that the risk of recurrent pancreatitis in a cohort of patients taking GLP-1 receptor agonists (10%) was likely no greater than what is observed in the general population and that more than half of the episodes of recurrent pancreatitis were attributable to causes other than GLP-1 receptor agonist therapy

Whether that is appropriate depends on individual goals and medical oversight