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The King's system uses five stages, from 1 to 5, and is based on disease burden, as measured by clinical involvement and significant feeding or respiratory failure, with stage 1 being symptom onset and stage 5 being death (Fang et al., 2017)

For semaglutide, common maintenance doses range from 0.25 mg to 1.0 mg weekly, down from the therapeutic 1.7 to 2.4 mg

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