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They primarily bind to GLP-1 receptors in brain areas controlling appetite and satiety

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Research highlight: A 2018 study in Nutrients found that astaxanthin supplementation (12mg/day for 12 weeks) actually increased glutathione levels in participants suggesting these two antioxidants work synergistically, not competitively (Chalyk et al., 2018)

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Leica, Wetzlar, Germany) using a Diamond knife (Diatome, Biel, Switzerland) and mounted on grids

In summary, our data provide new insights into the effects of tesofensine on weight loss and the underlying neuronal mechanisms, suggesting that tesofensine may be an effective treatment for obesity and that it may be a valuable adjunct to other appetite suppressants to prevent body weight rebound